Journal of Applicable Chemistry
نویسنده
چکیده
Accepted on 26 th December 2016, Published online on 27 th January 2017 _____________________________________________________________________________ ABSTRACT During the present investigation, a new series of 3,6-disubstituted[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives (3) were synthesized by refluxing a mixture of 3-substituted-4-amino-5-mercapto-1,2,4triazoles with substituted anilinoacetic acids in presence of phosphoryl chloride in good yield. The newly synthesized compounds were confirmed on the basis of elemental analyses, IR, 1 H NMR and Mass spectral data. All compounds were screened for their antibacterial and anti-fungal activity. Among the synthesized compounds (3c), (3f), (3g), (3j) and (3m) exhibited good antibacterial activity and antifungal activity.
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